Our High-Affinity Cyclodextrin Polymer (HACP) adsorbents provide the first practical and cost-effective means of removing hazardous micropollutants from the world’s drinking water supply.
Our family of patented HACPs utilize a proprietary nucleophilic substitution reaction to crosslink cyclodextrin with various rigid monomers to form an insoluble, high-surface area, mesoporous, cyclodextrin-based polymer network (P-CDP). Utilizing the distinct properties of cyclodextrin, our P-CDP adsorbents rapidly and selectively sequester trace levels of organic micropollutants from water - achieving equilibrium binding capacity in seconds with adsorption rate constants 15 - 200 greater than activated carbon. In addition, by using different rigid aromatic group crosslinkers, we can synthesize P-CDP formulations with targeted affinity for specified organic contaminant groups.

Our HACP materials leverage the adsorption properties of cyclodextrin.  Derived from corn, cyclodextrins are a family of enzymatically modified starches composed of glucose molecules bound together as a cyclic oligosaccharide. Typical cyclodextrins can be topologically represented as a three-dimensional toroid (concatenated cone) with a larger and smaller opening. This "cup-like" shape provides a distinct hydrophobic interior cavity which can form host-guest complexes with thousands of organic compounds.
CycloPure Science
High-Affinity Cyclodextrin Polymer (HACP) Adsorbents
Our patented technology combines cyclodextrin with rigid monomers to create a porous polymer network that allow rapid access by micropollutants to the binding properties of cyclodextrin "cups".
β Cyclodextrin
Rigid Monomer
Proprietary Polymerization Process
Porous High-Affinity
Cyclodextrin Polymer (HACP)
A hollow, three-dimensional structure, which forms a “cup” that can adsorb  organic micropollutants by forming a guest-host complex. In their native form, cyclodextrins are water soluble and are not practical water pollutant adsorbents.
β-cyclodextrin crosslinked with a rigid aromatic group resulting in a high-surface-area, mesoporous polymer of β-cyclodextrin that sequesters a variety of organic micropollutants with adsorption rate constants 15 to 200 times greater than those of activated carbons.
Breakthrough Technology
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